Usually these animals are maintained in germfree, gnotobiotic, or specificpathogenfree facilities. The atlas can also adapt body weight by changing body length and fat amount. Dec 27, 20 a practical guide to the histology of the mouse provides a fullcolour atlas of mouse histology. Information is provided about the anatomical features and landmarks for conducting a physical examination, collecting biological samples, making injections of therapeutic and experimental materials, using imaging modalities, and performing surgeries. A practical guide to the histology of the mouse provides a fullcolour atlas of mouse histology. A colour atlas of the anatomy of small laboratory animals. This atlas is fully articulated and can be positioned into arbitrary body poses.
Features fourcolor illustrations with complete instruction on mouse surgery, anatomy, behavior and care of the mouse in laboratory research offers additional chapters on new mouse strains, phenotyping of strains, bacteria and parasites, and immunology includes the newly revised eu standards on care, as well as, comparisons to standards and. Mice belong to the euarchontoglires clade, which includes humans. Mouse genome informatics the jackson laboratory bar harbor, maine april 2005 revised february 2008 table of contents subject index image index users guide. Microscopically, at the light, transmission and scanning electron microscopic. The discussion features an introduction to common laboratory mouse strains, including the nude mouse, whose genetic makeup renders them both hairless and immunodeficient.
The mouse hair coat is composed of two classes of hairs tactile and pelage. Laboratory animals centre carshalton, surrey, england. Describe the distinctive anatomical features of rats and mice. Take your mouse out of bag and spray, place on dissection tray already in the hood and spray mouse and bag with ethanol. The laboratory mouse handbook of experimental animals among animals used in research, teaching and testing, mice are now widely recognized as the most important model for human diseases and disorders.
American association for laboratory animal science. Infection of skin scratches and bite wounds with mouse or humanborne opportunistic microbes demands attention through a strict occupational medical treatment program national research council, 1997. Furthermore, efforts are currently underway to incorporate the adult mouse anatomy ontology into the national cancer institute nci thesaurus, a. With inclusions of the newly revised european standards on laboratory animals, this will be the most current, global authority on the care of mice in laboratory research. Anatomy and physiology of domestic animals, 2nd edition saunders veterinary anatomy flash cards 2nd edition comparative anatomy and histology a mouse, rat, and human atlas, 2nd. Ebook pdf ebook anatomy of the laboratory mouse, by. As a result, mouse colonies everywhere are expanding, and scientists who previously focused on other models are turning their attention to the mouse. The anatomy of the laboratory mouse bulbourethral gland. It guides the reader through normal mouse anatomy and histology using direct comparison to the human. Office for research shared and core facilities mouse histology and phenotyping laboratory. Features fourcolor illustrations with complete instruction on mouse surgery, anatomy, behavior and care of the mouse in laboratory research.
Endorsed by the american association of laboratory animal science aalas comparative anatomy of the mouse and rat. Cook never question with our deal, considering that we will certainly constantly provide what you need. Read download the laboratory mouse pdf pdf download. Historical foundations muriel t davisson and carol c linder 1 5 introduction 1 5 historical foundations 1 5 history of mouse genetics and research with the laboratory. Using pins from tray, secure the mouse to the tray at the shoulders and hips. Later the system will include a database of graphical geneexpression data. Aug 29, 2017 the second edition of comparative anatomy and histology is aimed at the new rodent investigator as well as medical and veterinary pathologists who need to expand their knowledge base into comparative anatomy and histology.
This paper presents a deformable mouse atlas of the laboratory mouse anatomy. Transgenic mouse models of amd is a more humanlike anatomy and physiology important. A brief history of mouse research is also offered, ranging from their first use in genetics experiments to nobel prizewinning discoveries in immunology and neurobiology. The laboratory mouse was derived from the common house mouse, mus musculus.
A mouse and human atlas is aimed at the new mouse investigator as well as medical and veterinary pathologists who need to expand their knowledge base into comparative anatomy and. Microscopically, at the light, transmission and scanning electron microscopic levels, the. Pdf ebook anatomy of the laboratory mouse, by margaret j. Development of the laboratory mouse began with pet fanciers who bred mice for their unique coat colors. These fancy mice then became subjects for research due to interest in the mechanisms of inheritance of these coat colors. The laboratory mouse handbook of experimental animals the laboratory mouse handbook of experimental animals the laboratory mouse, second edition is a comprehensive book written by international experts. Additionally the laboratory mouse continues to play a widely publicized vital role in the human genome project. No pains were spared to make this a perfect and readable description of the anatomy anatomy subject category. Mouse atlases mouse histology and phenotyping laboratory. The laboratory mouse is a small mammal of the order rodentia which is bred and used for scientific research.
Ocular anatomy and variations in laboratory animals. Information is provided about the anatomical features and landmarks for conducting a physical. Dried specimens were made to study the morphological form and internal structures. Experimental techniques on rodents, carnivores, birds, ruminants and monkeys are described. The topographical situation, mesenterial connections and arterial supply to the ceca were examined macroscopically. The primary audience for this work is biomedical researchers, laboratory animal veterinarians, and other professionals engaged in laboratory animal sciences, as well as, academic and research libraries. In pathbase, a database of mutant mouse pathology, anatomical attributes of images for mutant postnatal mouse pathology are coded using terms based on the adult mouse anatomical dictionary. Normally laboratory mice have to be involved by means of professional handlingrestraint in order to perform all procedures necessary during husbandry andor.
The anatomy of the cecum of the laboratory mouse and rat was studied from a comparative standpoint. Pelage hairs are associated with sebaceous glands and smooth muscle erector pili. Mouse models of disease are used extensively in biomedical research with many hundreds of new models being generated each year. Anatomy of the cecum of the laboratory mouse and rat. Laboratory mice are usually of the species mus musculus. This textbook would be a useful reference for laboratory animal. The laboratory mouse handbook of experimental animals usp.
Disciplines, occupations and industries see more details of the laboratory rat. The laboratory mouse handbook of experimental animals. The laboratory mouse is the most common used mammalian research model in biomedical research. Overall, i found this book to be very interesting, visually appealing, and a detailed exploration of the anatomy of the mouse and rat, with the differences between the species clearly highlighted in the text. The jackson laboratorys mission performing research. It guides the reader through normal mouse and rat anatomy and histology using direct comparison to the human.
Revised to reflect advances since the first edition, the laboratory mouse, second edition continues to be the most accessible reference on the biology and care of the laboratory mouse. The laboratory mouse, second edition is a comprehensive book written by international experts. The wistar bloodline has contributed more strains of rats than any other. Comparative anatomy and histology download ebook pdf, epub.
This public resource currently comprises two components. They are the most commonly used mammalian research model and are used for research in genetics, psychology, medicine and other scientific disciplines. The anatomy of the laboratory mouse mouse genome informatics. According to the preface, readers are assumed to have some knowledge of mammalian. There is a flap of skin from the removal of the other organs. Pdf guidelines for assessing the health and condition of mice. This textbook would be a useful reference for laboratory animal veterinarians and exotic animal practitioners. The second edition of comparative anatomy and histology is aimed at the new rodent investigator as well as medical and veterinary pathologists who need to expand their knowledge base into comparative anatomy and histology. Magnetic resonance mr imaging provides a method to obtain anatomical information from the brain.
Laboratory animals centre carshalton, surrey, england academic press 1965 adapted for the web by. Nov 24, 2012 pdf ebook anatomy of the laboratory mouse, by margaret j. Tactile hairs have associated venous sinuses, glands, and nerve endings. Felasa recommendations for the health monitoring of mouse, rat, hamster.
Very useful and detailed anatomy of dog, even the all information. There is a monkey bias in the ophthalmic drug delivery world because of the marked similarity between monkey and human eyes fovea accommodation outflow lids, tear film, orbital anatomy. One of the most timeconsuming activities in research laboratories is looking up information specific to the species or strain of animal being used. Col lection of body fluids, infusion techniques, care before, during and after surgery, radiography, euthanasia and disposal, parasitic infection, germfree techniques, aerosol challenge and drug administration are covered in this volume from basic techniques to refined special procedures. Comparative anatomy and histology sciencedirect histological staining is a series of technique processes undertaken in the preparation of sample tissues by staining using histological stains to aid in the microscope study anderson, 2011. Thank u for doing amazing program, i m waiting other part of body. For the researcher desiring a comprehensive reference concerning the laboratory mouse as a model system for observing health and disease processes, this book is an excellent choice. As like this updated book anatomy of the laboratory mouse, by margaret j. Normally laboratory mice have to be involved by means of professional handling restraint in order to perform all procedures necessary during husbandry andor. Chapter 1 origin of the laboratory mouse and related subspecies. Information is provided about the anatomical features and landmarks for conducting a physical examination, collecting. Reproductive biology of breeding mice womens health. Labeled crosssectional anatomy of the mouse on microct. A practical guide to the histology of the mouse wiley.